Dose 3: 100 mg/kg IV in 500 mL of diluent administered over 16 hours.Dose 2: 50 mg/kg IV in 250 mL of diluent administered over 4 hours.Loading dose: 150 mg/kg IV in 100 mL of diluent administered over 1 hour.

IV continuous infusion (Acetadote) weight over 20 kg to 39 kg:.Dose 3: 100 mg/kg in 14 mL diluent/kg body-weight over 16 hours.Dose 2: 50 mg/kg IV in 7 mL diluent/kg body-weight over 4 hours.Loading dose: 150 mg/kg IV in 3 mL diluent/kg body-weight over 1 hour.IV continuous infusion (Acetadote) weight less than 20 kg:.Weight over 100 kg: No specific studies have conducted limited data suggest a loading dose of 15,000 mg infused IV over 1 hour, then a first maintenance dose of 5,000 mg IV dose over 4 hours and a second maintenance dose of 10,000 mg over 16 hours.Dose 3: 100 mg/kg IV in 1000 mL D5W over 16 hours.Dose 2: 50 mg/kg IV in 500 mL D5W over 4 hours, then.Loading dose: 150 mg/kg IV mix in 200 mL of D5W and infuse over 1 hour.Acute ingestion (within 8-10 hour after ingestion).Maintenance dose: 4 hours after loading dose, start 70 mg/kg orally every 4 hours for a total 17 doses repeat dose if emesis occurs within 1 hour of administration.Intermittent IV infusion may be considered for late presenting or chronic ingestion (more than 10 hours after ingestion).Continuous IV infusion recommended for acute ingestion (ideally within 8-10 hour following ingestion, but may administer if more than 10 hours).What Are Dosages of Acetylcysteine (Antidote)?Įffervescent tablets for oral solution (Cetylev)

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